Dutch Connectome Lab

The dutch connectome lab is a group of neuroscience enthusiasts with all kinds of backgrounds (biology, physics, math, medicine, artificial intelligence) working at the Complex Trait Genetics Lab and the center for neurogenomics and cognitive research, part of the Neurocience Campus Amsterdam, VU Amsterdam and Amsterdam UMC.

Our focus: Integrative brain function depends on efficient functional communication within a massive web of billions to trillions of neuronal connections. All this is happening within what we call our 'brain'. Our research focus is to get a better understanding of the wiring architecture of the brain's network and to understand how abnormal connectivity may lead to neurological and psychiatric brain diseases. One of our recent pets is to map the communication hubs of the brain, examining how they 'rich club' together, at what price and, in particular, why... to keep our 1.5 kg of brain mush together?

Watch our research movie

People

These are the people of the Dutch Connetome Lab.

Papers

Recently published papers

  • Evolutionary modifications in human brain connectivity associated with schizophrenia
    van den Heuvel MP, Scholtens LH, de Lange SC, Pijnenburg R, Cahn W, van Haren NEM, Sommer IE, Bozzali M, Koch K, Boks MP, Repple J, Pievani M, Li L, Preuss TM, Rilling JK | Brain | 14-11-2019
  • Genetic mapping and evolutionary analysis of human-expanded cognitive networks
    Wei Y, de Lange SC, Scholtens LH, Watanabe K, Ardesch DJ, Jansen PR, Savage JE, Li L, Preuss TM, Rilling JK, Posthuma D, van den Heuvel MP | Nature Communications | 24-10-2019
  • Gradients of structure-function tethering across neocortex
    Vazquez-Rodriguez B1, Suarez LE, Markello RD, Shafiei G, Paquola C, Hagmann P, van den Heuvel MP, Bernhardt BC, Spreng RN, Misic B | Proceedings of the National Academy of Sciences | 30-09-2019
  • Topography Impacts Topology: Anatomically Central Areas Exhibit a "High-Level Connector" Profile in the Human Cortex
    Zhang J, Scholtens LH, Wei Y, van den Heuvel MP, Chanes L, Barrett LF, | Cerebral Cortex | 05-09-2019
  • Cross-sectional and longitudinal assessment of the upper cervical spinal cord in motor neuron disease
    van der Burgh HK, Westeneng H, Meier JM, van Es MA, Veldink JH, Hendrikse J, van den Heuvel MP, van den Berg LH | NeuroImage: Clinical | 16-08-2019

more... [ 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2006 | 2005 ]

Our favorites

  • Multimodal connectomics in psychiatry: bridging scales from micro to macro
    Scholtens LH, van den Heuvel MP | Biological Psychiatry: Cognitive Neuroscience and Neuroimaging | 19-04-2018
  • Comparative Connectomics
    van den Heuvel MP, Bullmore ET, Sporns O | Trends Cogn Sci. | 26-03-2016
  • The Neonatal Connectome During Preterm Brain Development
    van den Heuvel MP, Kersbergen KJ, de Reus MA, Keunen K, Kahn RS, Groenendaal F, de Vries LS, Benders MJ | Cereb Cortex. | 15-05-2014
  • Efficiency of functional brain networks and intellectual performance
    van den Heuvel MP, Stam CJ, Kahn RS, Hulshoff Pol HE | J Neurosci. | 10-06-2009
  • Functionally linked resting-state networks reflect the underlying structural connectivity architecture of the human brain
    van den Heuvel MP, Mandl RC, Kahn RS, Hulshoff Pol HE | Hum Brain Mapp | 23-02-2009

more... [ 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2006 | 2005 ]

Please let us know if you are looking for other resources or data.

Internship positions are available for highly motivated students, who are as excited as us to explore the connectome.

Lab members have wide variety of backgrounds and are working on a broad range of topics, so it is likely that there will be a project of interest for you. To give an impression, we list a few previous projects:

  • Linking connectomes from various modalities (EEG, resting state fMRI, DTI)
  • Studying different modalities of the developing brain
  • Exploring the microscopic connectome of the C. elegans
  • Relating genetics and connectomics in disorders
  • Developing new mathematical tools for network analysis
If you are interested, please contact us through the contact form on this website.

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