Dutch Connectome Lab

The dutch connectome lab is a group of neuroscience enthusiasts with all kinds of backgrounds (biology, physics, math, medicine, artificial intelligence) working at the Complex Trait Genetics Lab and the center for neurogenomics and cognitive research, part of the Neurocience Campus Amsterdam, VU Amsterdam and Amsterdam UMC.

Our focus: Integrative brain function depends on efficient functional communication within a massive web of billions to trillions of neuronal connections. All this is happening within what we call our 'brain'. Our research focus is to get a better understanding of the wiring architecture of the brain's network and to understand how abnormal connectivity may lead to neurological and psychiatric brain diseases. One of our recent pets is to map the communication hubs of the brain, examining how they 'rich club' together, at what price and, in particular, why... to keep our 1.5 kg of brain mush together?

Watch our research movie


These are the people of the Dutch Connetome Lab.


Recently published papers

  • Genetic mapping of cell type specificity for complex traits
    Watanabe K, Mirkov MU, de Leeuw CA, van den Heuvel MP, Posthuma D | Nature Communications | 19-07-2019
  • The human connectome from an evolutionary perspective
    Ardesch DJ, Scholtens LH, van den Heuvel MP | Progress in Brain Research | 09-07-2019
  • Connection strength of the macaque connectome augments topological and functional network attributes
    de Lange SC, Ardesch DJ, van den Heuvel MP | Network Neuroscience | 25-06-2019
  • Multi-scale neuroscience of psychiatric disorders
    van den Heuvel MP, Scholtens LH, Kahn RS | Biological psychiatry | 28-05-2019
  • A cross-disorder connectome landscape of brain dysconnectivity
    van den Heuvel MP, Sporns O. | Nature Reviews Neuroscience | 28-05-2019

more... [ 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2006 | 2005 ]

Our favorites

  • Multimodal connectomics in psychiatry: bridging scales from micro to macro
    Scholtens LH, van den Heuvel MP | Biological Psychiatry: Cognitive Neuroscience and Neuroimaging | 19-04-2018
  • Proportional thresholding in resting-state fMRI functional connectivity networks and consequences for patient-control connectome studies: Issues and recommendations
    van den Heuvel MP, de Lange SC, Zalesky A, Seguin C, Yeo T, Schmidt R | Neuroimage. | 01-02-2017
  • Connectome Disconnectivity and Cortical Gene Expression in Patients With Schizophrenia
    Romme IAC, de Reus MA, Ophoff RA, Kahn RS, van den Heuvel MP | Biol Psychiatry. | 27-07-2016
  • Rich club organization supports a diverse set of functional network configurations
    Senden M, Deco G, de Reus MA, Goebel R, van den Heuvel MP | Neuroimage. | 01-08-2014
  • An anatomical substrate for integration among functional networks in human cortex
    van den Heuvel MP, Sporns O | J Neurosci. | 04-09-2013

more... [ 2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2006 | 2005 ]

Please let us know if you are looking for other resources or data.

Internship positions are available for highly motivated students, who are as excited as us to explore the connectome.

Lab members have wide variety of backgrounds and are working on a broad range of topics, so it is likely that there will be a project of interest for you. To give an impression, we list a few previous projects:

  • Linking connectomes from various modalities (EEG, resting state fMRI, DTI)
  • Studying different modalities of the developing brain
  • Exploring the microscopic connectome of the C. elegans
  • Relating genetics and connectomics in disorders
  • Developing new mathematical tools for network analysis
If you are interested, please contact us through the contact form on this website.

Get in touch with the Dutch Connectome Lab. Send us an e-mail using this form.

Please, provide your name.
Please, provide a valid e-mail address.
Please, provide a message.
Sorry, those are not the first to decimals of Pi.