PhD student, department of neonatology Wilhelmina Children's Hospital, University Medical Center Utrecht and department of psychiatry, University Medical Center Utrecht
born: 5 April 1987
co-promotor: Manon Benders MD PhD, Martijn van den Heuvel PhD
My name is Kristin Keunen and my research project focuses on network development in (pre-)term infants. My interest in brain development in preterm infants arose during medical school, when I took an elective course in fetal brain development and subsequently participated in a research project on the effect of maternal sounds on (brain) development in preterm infants at the Department of Neonatology, Brigham and Women's Hospital in Boston, USA and thereafter in an elective research project on brain volumes in preterm infants at the Department of Neonatology, UMC Utrecht, under supervision of Dr. Manon Benders, Dr. Floris Groenendaal and Prof. Dr. Linda de Vries. I have ever since been intrigued by the impact of extreme prematurity and its complications on brain development and by the neurodevelopmental challenges the majority of preterm infants face during childhood and adolescence. The primary aim of my research is to help unravel how disturbances in neonatal brain development lead to cognitive impairments, using functional and structural network analyses. Furthermore, I am interested in healthy early network development.
This research project is a strong collaboration between the Department of Neonatology and the Department of Psychiatry, and it has been an honor to be able to learn from experts at both sites. The Department of Neonatology has specific and internationally renowned expertise in the field of neonatal neurology and has extensive experience in neonatal brain imaging, with a specific focus on MRI and advanced MRI techniques such as DTI and resting state functional MRI. The department of Psychiatry is one of the leading centers for network analyses. By combining knowledge of these two departments, we hope to contribute to a better understanding of the subtle disturbances in brain development that ultimately lead to cognitive and behavioral impairments later in life. This may help identify a much-needed window of opportunity for neuroprotective strategies.
2017• Cortical magnetization transfer abnormalities and connectome dysconnectivity in schizophrenia
Wei Y, Collin G, Mandl RCW, Cahn W, Keunen K, Schmidt R, Kahn RS, van den Heuvel MP | Schizophr Research | 01-06-2017
Keunen K, Benders MJ, Leemans A, van Haastert IC, Fieret-Stam PC, Scholtens LH, Viergever MA, Kahn RS, Groenendaal F, de Vries LS, van den Heuvel MP | Dev Med Child Neurol | 01-01-2017
Keunen K, Counsell SJ, Benders MJ | Neuroimage | 01-01-2017
2014• The Neonatal Connectome During Preterm Brain Development
van den Heuvel MP, Kersbergen KJ, de Reus MA, Keunen K, Kahn RS, Groenendaal F, de Vries LS, Benders MJ | Cereb Cortex. | 15-05-2014
2012• Brain tissue volumes in preterm infants: prematurity, perinatal risk factors and neurodevelopmental outcome: a systematic review
Keunen K, Kersbergen KJ, Groenendaal F, Isgum I, de Vries LS, Benders MJ | J Matern Fetal Neonatal Med. | 01-04-2012